Potassium citrate is a potassium salt of citric acid. It is rapidly absorbed when given orally and is excreted in the urine. Potassium citrate is an alkaline salt that makes the urine alkaline. As a result, it may be used to help minimise the formation of particular uroliths.
The alkalising effect of potassium citrate should be managed with care as highly alkaline urine may predispose patients to bacterial cystitis as well as the formation different uroliths.
Potassium citrate has been used for the prevention of calium oxalate uroliths. Citrate binds to urinary calcium to form calcium citrate, which is water-soluable and thus easily excreted in the urine.
Potassium citrate is a mineral salt.